Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ MMP-2 Substrate, Fluorogenic
A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1).
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MilliporeSigma™ Calbiochem™ α2-Macroglobulin, Human Plasma
A multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a trap around most proteases.
MilliporeSigma™ Calbiochem™ PARP Inhibitor I, 3-ABA
The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ NFAT Inhibitor
The NFAT Inhibitor controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ 8-Methoxymethyl-3-isobutyl-1-methylxanthine
A cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 μM).
MilliporeSigma™ Calbiochem™ p-Nitroblue Tetrazolium Chloride
NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 μM).
MilliporeSigma™ Calbiochem™ InSolution™ MG-132
InSolution™ MG-132, CAS 133407-82-6, is provided as a 10 mM solution in DMSO. Acts as a potent, reversible proteasome inhibitor (Ki = 4 nM).
MilliporeSigma™ Calbiochem™ MG-115
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
MilliporeSigma™ Calbiochem™ Mitochondrial Division Inhibitor, mdivi-1
The Mitochondrial Division Inhibitor, mdivi-1, also referenced under CAS 338967-87-6, controls the biological activity of yeast Dnm1 and mammalian Drp1.
MilliporeSigma™ Calbiochem™ CGP 7930
A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB recep
MilliporeSigma™ Calbiochem™ 11beta-HSD1 Inhibitor, 10j
The 11beta-HSD1 Inhibitor, 10j, also referenced under CAS 1009373-58-3, controls the biological activity of 11beta-HSD1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet
MilliporeSigma™ Calbiochem™ RAD51 Inhibitor, B02
The RAD51 Inhibitor, B02 controls the biological activity of RAD51. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ PARP Inhibitor IX, EB-47
The PARP Inhibitor IX, EB-47 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ MreB Perturbing Compound A22
A cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerization.